Production power.

Power and efficiency for large-scale genomics.

The HiSeq 2500 System is a powerful and efficient ultra-high-throughput sequencing system that supports the broadest range of applications and study sizes. Unrivaled data quality using Illumina's proven SBS chemistry has made the HiSeq 2500 the instrument of choice for all major genome centers and leading institutions throughout the world. New HiSeq v4 reagents allow for more reads and more data in less time.

Have questions about the HiSeq 2500? Contact a Sales Representative »

  • Announcing the Winner of the Love My HiSeq Reagent Offer

    See who won the HiSeq Reagents and check out what others have said about why they love their HiSeq System.

    See winner and quotes »
  • Longer Reads in Rapid Mode
    HiSeq v4 Reagent Kits

    New HiSeq v2 reagents for rapid run mode increase read lengths up to 2x250 bp.

    See the new kits »
  • Customers Happiest with HiSeq 2500

    Macquarie Research survey shows customers most satisfied with Illumina HiSeq 2500 compared to other sequencing systems.

    View the PDF »
  • New HCS software now available

    Learn how the new HiSeq Control Software (v2.2.38) increases data quality for low diversity samples, now available for all HiSeq systems.

    View the PDF »
    Download Software »

  • The Fastest Exome, Period.

    Sample to data in 2.5 days with the HiSeq 2500 ultra-high-throughput sequencer and Nextera Rapid Capture Exome.

    Watch the video »
    View exome sequencing data »

  • A new kind of bacterial transformation

    Sequencing confirms that certain bacterial species can integrate short, degraded DNA, even the ancient DNA of a woolly mammoth.

    Read the article »